Main Article Content
Abstract
Hypertension is a serious health risks for both the expectant mother and the fetus. It is crucial for concern in public health. Individuals with elevated arterial fluid conduit pressure significantly increase their chances of heart-related conditions and chronic kidney disease, accompanied by subsequent increase in death rate. This study assessed incidence of hypertension disorders among pregnant women in Port Harcourt Metropolis. A cross-sectional comparative study was employed. Eighty-two pregnant women (41 each from high environmentally exposed areas and low environmentally exposed areas). An authenticated partially-automated sphygmomanometer was used to ascertain participant’s blood pressure before enrolment. A subsequent reading was taken at most for two consecutive minutes when the first reading was ≥140 mmHg for peak arterial fluid conduit force (PBP) or ≥ 90 mmHg for resting arterial fluid conduit force (RBP). Descriptive statistics and independent t-tests were used to compare both groups, with statistical significance set at p < 0.05. Participants who met inclusion criterion where 41(50%) pregnant women from both environmentally exposed groups. New cases of hypertension were discovered in 36(87.8%) of participants from the former and 3(7.3%) from the later, while normotensive cases from the former were 5(12.2%) as against 38(92.7%) from the later. The cumulative incidence of hypertension in the former is 39(47.6%) of the whole population used for the research. Incidence of hypertension were more in participants from high environmentally exposed area than in the later. Routine comprehensive screening for hypertension in public and private health facilities is recommended.
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References
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- Ranaa, M. N., Tangponga, J., & Rahman, M. (2018). Toxicodynamics of lead, cadmium, mercury, and arsenic-induced kidney toxicity and treatment strategy: A mini review. Toxicology Reports, 5, 704–713.
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- Sazakli, E. (2024). Human health effects of oral exposure to chromium: A systematic review of the epidemiological evidence. International Journal of Environmental Research and Public Health, 21(4), 406.
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- Seely, E. W., & Ecker, J. (2014). Chronic hypertension in pregnancy. Circulation, 129(12), 1254–1261. https://doi.org/10.1161/CIRCULATIONAHA.113.003904
- Ubong, I. U., Obunwo, C., & Faafa, A. (2016, August). Essential and non-essential metals in soft drinks consumed and sold in Port Harcourt, Nigeria. RA Journal of Applied Research, 2(8). https://doi.org/10.18535/rajar/v2i8.04
- Vigeh, M., Yunesian, M., Shariat, M., Niroomanesh, S., & Ramezanzadeh, F. (2011). Environmental carbon monoxide related to pregnancy hypertension. Women & Health, 51(8), 724–738.
- Wan, E. Y. F., Yu, E. Y. T., Chin, W. Y., Fong, D. Y. T., Choi, E. P. H., & Lam, C. L. K. (2019). Association of blood pressure and risk of cardiovascular and chronic kidney disease in Hong Kong hypertensive patients. Hypertension, 74, 331–340. https://doi.org/10.1161/HYPERTENSIONAHA.119.13123
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References
Agrawal, A., & Wenger, N. K. (2020). Hypertension during pregnancy. Current Hypertension Reports, 22, 64. https://doi.org/10.1007/s11906-020-01070-0
Amin, K. A., Homeida, A. M., El Mazoudy, R. H., Hashim, K. S., & Garelnabi, M. (2019). Dietary lipids in health and disease. Journal of Lipids, 2019, 5729498. https://doi.org/10.1155/2019/5729498
Dominici, F., Zanobetti, A., Schwartz, J., Braun, D., Sabath, B., Wu, X. (2022). Assessing adverse health effects of long-term exposure to low levels of ambient air pollution: Implementation of causal inference methods. Research Reports Health Effects Institute, 2022(211), 1–56. PMID: 36193708; PMCID: PMC9530797.
Fraser, A., & Catov, J. M. (2023). Placental syndromes and long-term risk of hypertension. Journal of Human Hypertension, 37(7), 671–674. https://doi.org/10.1038/s41371-023-00802-4
Gambelunghe, A., Sallsten, G., Borné, Y., Forsgard, N., Hedblad, B., Nilsson, P. (2016). Low-level exposure to lead, blood pressure, and hypertension in a population-based cohort. Environmental Research, 149, 157–163. https://linkinghub.elsevier.com/retrieve/pii/S0013935116301876
Ifenkwe, J. C., Nwanjo, H. U., Nwosu, D. C., Solomon, E. A., & Bot, Y. S. (2018). Heavy metal bioaccumulation and lipid peroxidation damage in residents of a gas flaring community. International Journal of Advances in Scientific Research and Engineering, 4(7). https://doi.org/10.31695/IJASRE.2018.32810
Liu, X., Ruan, Y., Liu, Y., & Zhang, W. (2015). Relationship between maternal age and hypertensive disorders in pregnancy. Zhonghua Yi Xue Za Zhi, 95(1), 19–22. [In Chinese]. PMID: 25876802.
Min, K. S., Sano, E., Ueda, H., Sakazaki, F., Yamada, K., Takano, M., & Tanaka, K. (2015). Dietary deficiency of calcium and/or iron, an age-related risk factor for renal accumulation of cadmium in mice. Biological & Pharmaceutical Bulletin, 38(10), 1557–1563. https://doi.org/10.1248/bpb.b15-00362
National Institute of Environmental Health Sciences. (2024). Exposure Science. Retrieved from https://www.niehs.nih.gov/health/topics/science/exposure
Nguyen, H. L., Leermakers, M., Osan, J., Torok, S., & Baeyens, W. (2005). Heavy metals in Lake Balaton: Water column, suspended matter, sediment, and biota. Science of the Total Environment, 340(1–3), 213–230. https://doi.org/10.1016/j.scitotenv.2004.07.032
Poon, L. C., Nguyen-Hoang, L., Smith, G. N., Bergman, L., O'Brien, P., Hod, M., ... Jacobsson, B. (2023). Hypertensive disorders of pregnancy and long-term cardiovascular health: FIGO best practice advice. International Journal of Gynecology & Obstetrics, 1–9. https://doi.org/10.1002/ijgo.14540
Rana, S., Lemoine, E., Granger, J. P., & Karumanchi, S. A. (2019). Preeclampsia: Pathophysiology, challenges, and perspectives. Circulation Research, 124(7), 1094–1112.
Ranaa, M. N., Tangponga, J., & Rahman, M. (2018). Toxicodynamics of lead, cadmium, mercury, and arsenic-induced kidney toxicity and treatment strategy: A mini review. Toxicology Reports, 5, 704–713.
Roeters van Lennep, J. E., Tokgözoğlu, L. S., Badimon, L. (2023). Women, lipids, and atherosclerotic cardiovascular disease: A call to action from the European Atherosclerosis Society. European Heart Journal, 44, 4157–4173.
Savitz, D. A., Stein, C. R., Elston, B. (2012). Relationship of perfluorooctanoic acid exposure to pregnancy outcome based on birth records in the mid-Ohio Valley. Environmental Health Perspectives, 120(8), 1201–1207. https://doi.org/10.1289/ehp.1104752
Sazakli, E. (2024). Human health effects of oral exposure to chromium: A systematic review of the epidemiological evidence. International Journal of Environmental Research and Public Health, 21(4), 406.
Sears, C. G., Braun, J. M., Ryan, P. H., Xu, Y. Y., Werner, E. F., Lanphear, B. P. (2018). The association of traffic-related air and noise pollution with maternal blood pressure and hypertensive disorders of pregnancy in the HOME study cohort. Environmental International, 121, 574–581.
Seely, E. W., & Ecker, J. (2014). Chronic hypertension in pregnancy. Circulation, 129(12), 1254–1261. https://doi.org/10.1161/CIRCULATIONAHA.113.003904
Ubong, I. U., Obunwo, C., & Faafa, A. (2016, August). Essential and non-essential metals in soft drinks consumed and sold in Port Harcourt, Nigeria. RA Journal of Applied Research, 2(8). https://doi.org/10.18535/rajar/v2i8.04
Vigeh, M., Yunesian, M., Shariat, M., Niroomanesh, S., & Ramezanzadeh, F. (2011). Environmental carbon monoxide related to pregnancy hypertension. Women & Health, 51(8), 724–738.
Wan, E. Y. F., Yu, E. Y. T., Chin, W. Y., Fong, D. Y. T., Choi, E. P. H., & Lam, C. L. K. (2019). Association of blood pressure and risk of cardiovascular and chronic kidney disease in Hong Kong hypertensive patients. Hypertension, 74, 331–340. https://doi.org/10.1161/HYPERTENSIONAHA.119.13123
World Health Organization. (2023). Hypertension. Retrieved March 19, 2025, from https://www.who.int/news-room/fact-sheets/detail/hypertension.